Thermo Scientific™ BS2G-d0 (bis(sulfosuccinimidyl) glutarate-d0)

Description

Crosslink amines to amines using these heavy (deuterated) and light matched pairs of a 7.7A, NHS-ester crosslinker for mass spectrometry analysis of protein interactions.

Thermo Scientific™ Pierce BS2G-d0/d4 reagents form a matched set of heavy (deuterated) and light mass varieties of a short, amine-reactive crosslinker that facilitates the identification of crosslinked peptides by mass spectrometry.

Highlights:

• Well-characterized, high-purity, deuterium-labeled crosslinker and its hydrogen-containing analog
• Instructions edited by an expert in the crosslinking/MS strategy field
• Suberate- and glutarate-based reagent pair - provides a “molecular ruler” option to study inter- and intra-molecular distances to gain structural information not possible with just one reagent
• Efficient and convenient - requires only microgram amounts of protein; an excellent alternative to NMR or X-ray crystallography-based methods that require large amounts of protein, special solvents or crystal formation
• Reactive groups: Sulfo-NHS ester (homobifunctional)
• Reactive toward: amino groups

Specifications

• Chemical Reactivity: Amine-Amine
• Cleavable: No
• Description: BS2G-d0
• Molecular Weight (g/mol): 530.35
• PEGylated: No
• Spacer Arm Length: 7.7 Å
• Content And Storage: Upon receipt store desiccated at 4 to 8°C.
• Cell Permeability: No
• Shipping Condition: Ambient
• Product Line: Pierce™
• Labeling Method: Chemical Labeling
• Crosslinker Type: Homobifunctional
• Reactive Moiety: Sulfo-NHS Ester
• Spacer: Short (<10 Å)
• Form: Powder
• Quantity: 10 mg
• Solubility: Water
• Format: Standard
• Water Soluble: Yes
• Product Type: Crosslinker

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.