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Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Catalog No. pi21655
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50 mg
10 x 2 mg
1 g
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Catalog No. Quantity
PI21655 50 mg
PIA39267 10 x 2 mg
PI21555 1 g
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Catalog No. PI21655 Supplier Thermo Scientific™ Supplier No. 21655
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Description

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

Highlights:

  • Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Crosslink oriented antibodies to Protein A or G agarose
  • Immobilize proteins onto amine-coated surfaces
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Amine
Cleavable No
Description DSS
Molecular Weight (g/mol) 368.35
PEGylated No
Spacer Arm Length 11.4 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety NHS Ester
Spacer Medium (10 to 30 Å)
Form Powder
Quantity 50 mg
Solubility DMF, DMSO
Format Standard, Single-use
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.

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