Thermo Scientific™ EGS (ethylene glycol bis(succinimidyl succinate))

Description

Crosslink amines to amines with this membrane permeable crosslinker composed of NHS-ester groups and a 16.1A hydroxylamine-cleavable spacer arm.

Thermo Scientific™ Pierce EGS is a crosslinker that contains amine-reactive NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5.

Highlights:

• Cleavable at pH 8.5 using Hydroxylamine for 3-6 hours at 37°C
• Lactose dehydrogenase retained 60% of its activity after reversible crosslinking with EGS
• Reactive groups: NHS esters (homobifunctional)
• Reactive toward: amino groups

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Specifications

• Chemical Reactivity: Amine-Amine
• Cleavable: By Hydroxylamine
• Description: EGS
• Molecular Weight (g/mol): 456.36
• PEGylated: No
• Spacer Arm Length: 16.1 Å
• Content And Storage: Upon receipt store at 4°C.
• Cell Permeability: Yes
• Shipping Condition: Ambient
• Product Line: Pierce™
• Labeling Method: Chemical Labeling
• Crosslinker Type: Homobifunctional
• Reactive Moiety: NHS Ester
• Spacer: Medium (10 to 30 Å)
• Form: Powder
• Quantity: 1 g
• Solubility: DMF, DMSO
• Format: Standard
• Water Soluble: No
• Product Type: Crosslinker

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.