Thermo Scientific™ EMCH (N-ε-maleimidocaproic acid hydrazide)

Description

Crosslink sulfhydryls to periodate-treated glycoprotein sugars with this mid-length (11.8A) crosslinker containing maleimide and hydrazide groups.

Thermo Scientific™ Pierce EMCH is a mid-length, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Highlights:

• Sulfhydryl- and oxidized carbohydrate-reactive agent
• Covalently couple the hydrazide group of EMCH to glycoproteins and other glycoconjugates after oxidation with sodium meta-periodate
• Reactive groups: maleimide and hydrazide
• Reactive toward: sulfhydryl and carbonyl (oxidized carbohydrate) groups
• Use with EDC for reactivity toward carboxyl groups

Specifications

• Chemical Reactivity: Carbohydrate-Sulfhydryl
• Cleavable: No
• Description: EMCH
• Molecular Weight (g/mol): 339.29
• PEGylated: No
• Spacer Arm Length: 11.8 Å
• Content And Storage: Upon receipt store desiccated at 4°C.
• Cell Permeability: Yes
• Shipping Condition: Ambient
• Product Line: Pierce™
• Labeling Method: Chemical Labeling
• Crosslinker Type: Heterobifunctional
• Reactive Moiety: Amine, Hydrazide, Maleimide
• Spacer: Medium (10 to 30 Å)
• Form: Solid
• Quantity: 50 mg
• Solubility: Water
• Format: Standard
• Water Soluble: Yes
• Product Type: Crosslinker

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.