Invitrogen™ PIG3 Monoclonal Antibody (10A2)

Catalog No.	Quantity
01-674-338	100 μg

Catalog No. 01-674-338 Supplier Invitrogen™ Supplier No. MA112548

Description

Mouse Monoclonal Antibody

A suggested positive control for this product is Jurkat cell lysate.

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: PIG3
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 10A2
• Conjugate: Unconjugated
• Formulation: PBS with 0.08% sodium azide
• Gene: TP53I3
• Gene Accession No.: Q53FA7
• Gene Alias: p53-induced gene 3 protein; PIG3; quinone oxidoreductase homolog; quinone oxidoreductase PIG3; Quinone oxidoreductase-like protein 2; RGD1304982; TP53I3; tumor protein p53 inducible protein 3; Tumor protein p53-inducible protein 3
• Gene Symbols: TP53I3
• Host Species: Mouse
• Immunogen: Recombinant human PIG-3 protein.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9540
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1