Invitrogen™ PIG3 Monoclonal Antibody (10A2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA112548

Catalog No. 01-674-338

Description

A suggested positive control for this product is Jurkat cell lysate.

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: PIG3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TP53I3
• Gene Alias: p53-induced gene 3 protein; PIG3; quinone oxidoreductase homolog; quinone oxidoreductase PIG3; Quinone oxidoreductase-like protein 2; RGD1304982; TP53I3; tumor protein p53 inducible protein 3; Tumor protein p53-inducible protein 3
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 9540
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Clone: 10A2
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: Q53FA7
• Gene Symbols: TP53I3
• Immunogen: Recombinant human PIG-3 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1