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Invitrogen™ PIGW Polyclonal Antibody
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Catalog No. PIPA5104012
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100 μL
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PIPA5104012 100 μL
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Catalog No. PIPA5104012 Supplier Invitrogen™ Supplier No. PA5104012
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PIGW.

Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid multi-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIGW
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PIGW
Gene Accession No. Q7Z7B1
Gene Alias 2610044A17Rik; Gwt1; HPMRS5; phosphatidylinositol glycan anchor biosynthesis class W; phosphatidylinositol glycan anchor biosynthesis, class W; phosphatidylinositol glycan, class W; phosphatidylinositol-glycan biosynthesis class W protein; Pigw; PIG-W
Gene Symbols PIGW
Host Species Rabbit
Immunogen A synthesized peptide derived from human PIGW(Accession Q7Z7B1), corresponding to amino acid residues F132-C182.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 284098
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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