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Invitrogen™ Human PIK3C2G (PI3K-C2 gamma), GST Tag Recombinant Protein

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Quantity:
1 mg
100 μg
20 μg
Description
PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.

Specifications
Specifications
Accession Number | O75747 |
Concentration | See Label |
For Use With (Application) | Kinase Assay |
Formulation | 50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5 |
Gene ID (Entrez) | 5288 |
Molecular Weight (g/mol) | 110 kDa |
Name | Human PIK3C2G (PI3K-C2 gamma), GST Tag |
Quantity | 1 mg |
Gene Alias | C80387; phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma; phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI 3-kinase C2gamma; PI3KC2gamma; PI3K-C2gamma; PI3K-C2-gamma; Pik3c2g; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma |
Common Name | PIK3C2G |
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