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Invitrogen™ PIM1 Recombinant Superclonal™ Antibody (19HCLC)

Catalog No. PI710504
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100 μg
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Catalog No. Quantity
PI710504 100 μg
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Catalog No. PI710504 Supplier Invitrogen™ Supplier No. 710504
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Description

Rabbit Recombinant Superclonal Antibody

This antibody is predicted to react with bovine, canine, equine, feline, non-human primate, mouse, rabbit, ovine and porcine based on sequence homology. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called 'Recombinant polyclonal antibody', this product is now rebranded as 'Recombinant Superclonal™ antibody'. The physical product and the performance remain unchanged.

The proto-oncogene PIM1 is upregulated in prostate cancer. PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIM1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Superclonal
Clone 19HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene PIM1
Gene Accession No. P06803, P11309
Gene Alias non-specific serine/threonine protein kinase; Oncogene PIM1; PIM; Pim1; Pim-1; pim-1 kinase 44 kDa isoform; pim-1 oncogene; pim-1 oncogene (proviral integration site 1); Pim-1 proto-oncogene, serine/threonine kinase; proto-oncogene serine/threonine-protein kinase Pim-1; proviral integration site 1; serine/threonine-protein kinase pim-1; serine-threonine kinase PIM-1
Gene Symbols PIM1
Host Species Rabbit
Immunogen Peptide corresponding to amino acids 115-130 of human PIM-1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18712, 5292
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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