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Invitrogen™ PIM2 Polyclonal Antibody
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Catalog No. PIPA5104127
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100 μL
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PIPA5104127 100 μL
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Catalog No. PIPA5104127 Supplier Invitrogen™ Supplier No. PA5104127
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PIM2.

PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIM2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PIM2
Gene Accession No. Q62070, Q9P1W9
Gene Alias DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2
Gene Symbols PIM2
Host Species Rabbit
Immunogen A synthesized peptide derived from human PIM2(Accession Q9P1W9), corresponding to amino acid residues M1-G49.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11040, 18715, 317366
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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