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Tocris Bioscience™ Pimavanserin
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Catalog No. 766750
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76-675-0 50 mg
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Catalog No. 76-675-0 Supplier Tocris Bioscience™ Supplier No. 7667/50
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Description

Selective 5-HT2A inverse agonist

Pimavanserin (also known as ACP-103) is a selective, potent 5-HT2A receptor inverse agonist (IC50 = 2 nM). Pimavanserin displays ∼ 40-fold higher affinity for 5-HT2A over 5-HT2C receptor. Chronic administration of Pimavanserin, suppresses amyloid-β production and improves anxiety-related behavior and memory in Alzheimer's disease mouse models. Pimavanserin shows protective effects on midbrain dopaminergic neurons in a rat model of Parkinson's Disease.

Specifications

Chemical Name or Material N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]urea
CAS 706779-91-1
Quantity 50 mg
Target 5-HT2A Receptor Antagonists
Molecular Formula C25H34FN3O2
Purity 98%
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