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PIN1 Monoclonal Antibody (OTI4H1), TrueMAB™, OriGene
SDP

Catalog No. 501684482
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100 μL
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Catalog No. Quantity
50-168-4482 100 μL
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Catalog No. 50-168-4482 Supplier OriGene Supplier No. TA812247
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Description

Mouse Monoclonal Antibody

Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.

Specifications

Antigen PIN1
Applications Western Blot
Classification Monoclonal
Clone OTI4H1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene PIN1
Gene Accession No. Q13526
Gene Alias DOD, UBL5
Gene Symbols PIN1
Host Species Mouse
Immunogen Full length human recombit protein of human PIN1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 298696, 5300
Target Species Human, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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