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PIN1 Monoclonal Antibody (OTI4H1), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA812247

Encompass_Preferred

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Catalog No. 50-168-4482


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Description

Description

Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
Specifications

Specifications

PIN1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q13526
PIN1
Full length human recombit protein of human PIN1 produced in E.coli.
100 μL
Primary
Human, Rat
Antibody
IgG1
Western Blot
OTI4H1
Unconjugated
PIN1
DOD, UBL5
Mouse
Affinity Chromatography
RUO
298696, 5300
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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