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Invitrogen™ PINK1 Polyclonal Antibody
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Catalog No. APPA6604
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100 μL
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APPA6604 100 μL
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Catalog No. APPA6604 Supplier Invitrogen™ Supplier No. PA116604
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Rabbit Polyclonal Antibody

PINK1 Polyclonal Antibody for Western Blot, ICC/IF

PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes. The kinase domain of PINK1 appears to be critical in its protective effects. Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress. Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes. When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson's disease are triggered.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PINK1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PINK1
Gene Accession No. B5DFG1, Q99MQ3, Q9BXM7
Gene Alias 1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial
Gene Symbols PINK1
Host Species Rabbit
Immunogen N-terminal region synthetic peptide made to the human PINK1 protein sequence (between residues 1-50).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 298575, 65018, 68943
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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