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Enzo Life Sciences Pioglitazone (5mg). CAS: 111025-46-8
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Supplier:  Enzo Life Sciences ALX270367M005

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Pioglitazone selectively activates PPARγ-1. It is about one tenth as potent as rosiglitazone (EC50~500nM for human and mouse PPARγ). In a transactivation assay using COS-1 cells transfected with full length human PPARα and RXRα, pioglitazone and rosiglitazone exhibit low level activation of PPARα at 1µM and 5.4- and 4.2-fold activation, respectively, at a concentration of 10µM. Formula: C19H20N2O3S. MW: 356.4. MI: 14: 7452. Purity: ≥97% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in DMSO (2.5mg/ml) or dimethyl formamide (2.5mg/ml). Long Term Storage: -20°C. Handling: Protect from moisture.

Catalog No. 50-200-8513


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