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Invitrogen™ Pirh2 Monoclonal Antibody (1H10)
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Catalog No. PIMA515596
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100 μL
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Catalog No. Quantity
PIMA515596 100 μL
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Catalog No. PIMA515596 Supplier Invitrogen™ Supplier No. MA515596
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Description

Mouse Monoclonal Antibody

MA5-15596 targets Pirh2 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and Rat samples. The MA5-15596 immunogen is purified recombinant fragment of human Pirh2 expressed in E. Coli. MA5-15596 detects Pirh2 which has a predicted molecular weight of approximately 30kDa; 60kDa (homodimer).

The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pirh2
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1H10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene RCHY1
Gene Accession No. Q96PM5
Gene Alias Androgen receptor N-terminal-interacting protein; androgen-receptor N-terminal-interacting protein; ARNIP; Chimp; CH-rich interacting match with PLAG1; CH-rich-interacting match with PLAG1; DKFZp586C1620; E3 ubiquitin-protein ligase Pirh2; h PRO1996; hPirh2; p53-induced protein with a RING-H2 domain; p53-induced RING-H2 protein; PIRH2; PIRH2E; PIRH2F; PRO1996; RCHY1; ring finger and CHY zinc finger domain containing 1; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; Zfp363; Zinc finger protein 363; zinc finger, CHY-type; Znf363
Gene Symbols RCHY1
Host Species Mouse
Immunogen Purified recombinant fragment of human Pirh2 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25898, 289508
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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