Invitrogen™ Pirh2 Monoclonal Antibody (1H10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515596

Catalog No. PIMA515596

Description

MA5-15596 targets Pirh2 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and Rat samples. The MA5-15596 immunogen is purified recombinant fragment of human Pirh2 expressed in E. Coli. MA5-15596 detects Pirh2 which has a predicted molecular weight of approximately 30kDa; 60kDa (homodimer).

The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Pirh2
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: Q96PM5
• Gene Symbols: RCHY1
• Immunogen: Purified recombinant fragment of human Pirh2 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 25898, 289508
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 1H10
• Conjugate: Unconjugated
• Gene: RCHY1
• Gene Alias: Androgen receptor N-terminal-interacting protein; androgen-receptor N-terminal-interacting protein; ARNIP; Chimp; CH-rich interacting match with PLAG1; CH-rich-interacting match with PLAG1; DKFZp586C1620; E3 ubiquitin-protein ligase Pirh2; h PRO1996; hPirh2; p53-induced protein with a RING-H2 domain; p53-induced RING-H2 protein; PIRH2; PIRH2E; PIRH2F; PRO1996; RCHY1; ring finger and CHY zinc finger domain containing 1; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; Zfp363; Zinc finger protein 363; zinc finger, CHY-type; Znf363
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1