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PITPNB Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501570829
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50-157-0829 20 μL
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Catalog No. 50-157-0829 Supplier Bethyl Laboratories, Inc Supplier No. A305591AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine

The lipid binding proteins known as phosphatidylinositol transfer proteins (PITP) facilitate the formation of phosphatidylinositol derived second messenger molecules, which are related to the phospholipase C and phosphoinositide 3-kinase pathways. PITP are ubiquitously expressed proteins that transfer phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes enriched in PI or PC to membranes that are deficient in PI or PC. PITP mobilizes PI from the endoplasmic recticulum and regulates the release of PI from stored vesicles in the Golgi network. In mammalian cells, three smaller forms of soluble PITP are present, designated PITP alpha, PITP beta and retinal degeneration B (rdgB) beta. PITP beta is a 271 amino acid protein that is widely expressed in various tissues. Though required for Golgi targeting, constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity. There are two isoforms of PITP beta that are produced as a result of alternative splicing events.

Specifications

Antigen PITPNB
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PITPNB
Gene Accession No. P48739, P53811
Gene Alias PI-TP-beta, PtdInsTP, VIB1B, PtdIns transfer protein beta, phosphatidylinositol transfer protein beta isoform, phosphotidylinositol transfer protein, beta, ptdInsTP beta
Gene Symbols Pitpnb
Host Species Rabbit
Immunogen Between 221 and 271
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23760, 56305
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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