PKC zeta Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5494	150 μL

Catalog No. 50-173-5494 Supplier Proteintech Group Inc Supplier No. 268991AP150UL

Description

Rabbit Polyclonal Antibody

PKC zeta is a member of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differ among tissues and PKC family member exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca2+.

Specifications

• Antigen: PKC zeta
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.33 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PRKCZ
• Gene Accession No.: Q02956, Q05513
• Gene Alias: PKC ZETA, PKC2, PRKCZ, Protein kinase C zeta type, protein kinase C, zeta
• Gene Symbols: Prkcz
• Host Species: Rabbit
• Immunogen: PKC zeta Fusion Protein Ag25391
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18762, 5590
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG