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PKLR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501733870 Shop All Proteintech Group Inc Products
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50-173-3870 150 μL
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Catalog No. 50-173-3870 Supplier Proteintech Group Inc Supplier No. 224561AP150UL
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Rabbit Polyclonal Antibody

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen PKLR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.61 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PKLR
Gene Accession No. P12928, P30613, P53657
Gene Alias PK1, PKL, PKLR, PKR, PKRL, Pyruvate kinase 1, Pyruvate kinase isozymes R/L, pyruvate kinase, liver and RBC, R type/L type pyruvate kinase, Red cell/liver pyruvate kinase, RPK
Gene Symbols Pklr
Host Species Rabbit
Immunogen PKLR Fusion Protein Ag17933
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18770, 24651, 5313
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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