PKM2 Mouse anti-Human, Mouse, Rat, Clone: 1C11C7, Proteintech

Catalog No.	Quantity
50-173-6365	150 μL

Catalog No. 50-173-6365 Supplier Proteintech Group Inc Supplier No. 602681IG150UL

Description

Mouse Monoclonal Antibody

PKM2, Pyruvate kinase isozymes M1/M2, has 2 isoforms. The immunogen of this antibody is M2 isoform, also called PKM2.

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.

Specifications

• Antigen: PKM2
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Classification: Monoclonal
• Clone: 1C11C7
• Concentration: 0.53 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: PKM
• Gene Accession No.: P11980, P14618, P52480
• Gene Alias: CTHBP, OIP 3, OIP3, Opa interacting protein 3, p58, PK2, PK3, PKM, PKM1, PKM2, PKM2 pyruvate kinase, muscle, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, TCB, THBP1, Tumor M2 PK
• Gene Symbols: PKM
• Host Species: Mouse
• Immunogen: Peptide
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18746, 25630, 5315
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1