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Invitrogen™ PKN1 Polyclonal Antibody
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Catalog No. PIPA575550
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100 μL
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PIPA575550 100 μL
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Catalog No. PIPA575550 Supplier Invitrogen™ Supplier No. PA575550
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can also be activated by phospholipids. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKN1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene PKN1
Gene Accession No. P70268, Q16512, Q63433
Gene Alias DBK; F730027O18Rik; PAK1; PAK-1; PKN; PKN1; PKN-ALPHA; PRK1; Prkcl1; Protease-activated kinase 1; protein kinase C-like 1; Protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; serine/threonine kinase 3; serine/threonine protein kinase N; serine/threonine-protein kinase N1; serine-threonine kinase N; serine-threonine protein kinase N; Stk3
Gene Symbols PKN1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 294-339 of Human PKN1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29355, 320795, 5585
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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