Invitrogen™ PKP3 Monoclonal Antibody (23E3/4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 357600

Catalog No. 35-760-0

Description

PKP3 Monoclonal Antibody for Western Blot, IHC, IP, ELISA

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.

Specifications

• Antigen: PKP3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: Q9Y446
• Gene Symbols: PKP3
• Immunogen: Synthetic peptide from Armadillo domain of human Plakophilin-3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: 23E3/4
• Conjugate: Unconjugated
• Gene: PKP3
• Gene Alias: 2310056L12Rik; Pkp3; plakophilin 3; plakophilin 3b; plakophilin-3
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11187
• Content And Storage: -20°C
• Form: Liquid