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Invitrogen™ PKP3 Monoclonal Antibody (23E3/4)
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Catalog No. 357600
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Catalog No. Quantity
35-760-0 100 μg
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Catalog No. 35-760-0 Supplier Invitrogen™ Supplier No. 357600
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Description

Mouse Monoclonal Antibody

PKP3 Monoclonal Antibody for Western Blot, IHC, ELISA, IP

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKP3
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 23E3/4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene PKP3
Gene Accession No. Q9Y446
Gene Alias 2310056L12Rik; Pkp3; plakophilin 3; plakophilin 3b; plakophilin-3
Gene Symbols PKP3
Host Species Mouse
Immunogen Synthetic peptide from Armadillo domain of human Plakophilin-3.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11187
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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