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  5. Tocris Bioscience™ PKUMDL WQ 2201

Tocris Bioscience™ PKUMDL WQ 2201

Catalog No. 65815
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5 mg
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Catalog No. Quantity
65-815 5 mg
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Catalog No. 65-815 Supplier Tocris Bioscience™ Supplier No. 6581/5
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Description

Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)

PKUMDL WQ 2201 is a negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 35.7 μM). Displays dose-dependent suppression of cell viability in a range of cancer cell lines. Inhibits tumor growth in a xenograft mouse model.

Specifications

Chemical Name or Material 2-Chloro-4-[5-[[2-[(ethylamino)thioxomethyl]hydrazinylidene]methyl]-2-furanyl]benzoic acid
CAS 592474-91-4
Quantity 5 mg
Molecular Formula C15H14ClN3O3S
Formula Weight 351.81
Purity 98%
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