Invitrogen™ PLA2G4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5111304	Invitrogen™ PA5111304	100 μL
PIPA5111389	Invitrogen™ PA5111389	100 μL

Description

Immunogen sequence: PRETEEEKEI ADFDIFDDPE SPFSTFNFQY PNQAFKRLHD LMHFNTLNNI DVIKEAMVES IEYRRQNPSR CSVSLSNVEA RRFFNKEFLS K.

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Specifications

• Antigen: PLA2G4A
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P47712
• Gene ID (Entrez): 5321
• Immunogen: Recombinant Protein corresonding to Human PLA2G4A. Recombinant protein control fragment (Product #RP-103063).
• Product Type: Antibody

• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: PLA2G4A
• Gene Alias: calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A
• Gene Symbols: PLA2G4A
• Primary or Secondary: Primary
• Purification Method: Antigen Affinity Chromatography