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Invitrogen™ Plexin-A1 Polyclonal Antibody
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Catalog No. PIPA5143745
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100 μL
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PIPA5143745 100 μL
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Catalog No. PIPA5143745 Supplier Invitrogen™ Supplier No. PA5143745
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Description

Rabbit Polyclonal Antibody

The antibody detects a 220 kDa* protein corresponding to the apparent molecular mass of Plexin-A1 on SDS-PAGE immunoblots of neonatal rat brain and Cos-7 cells transfected with mouse Plexin-A1. In immunocytochemistry, this antibody co-localizes with anti-Myc in Cos-7 cells transfected with Myc-tagged mouse Plexin-A1.

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Plexin-A1
Applications Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.75 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene PLXNA1
Gene Accession No. P70206, Q9UIW2
Gene Alias 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; plexin-A1; PLXN1; Plxna1; RGD1560871; semaphorin receptor NOV
Gene Symbols PLXNA1
Host Species Rabbit
Immunogen Plexin-A1 synthetic peptide (coupled to carrier protein) corresponding to a region within the N-terminal half of the semaphorin domain in human Plexin-A1. This sequence is highly conserved in rat and mouse Plexin-A1, and has low homology to other Plexin family members.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18844, 362398, 5361
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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