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  6. Invitrogen™ Plexin-B2 Monoclonal Antibody (eBio3E7 (3E7)), eBioscience™, Invitrogen™ 

Invitrogen™ Plexin-B2 Monoclonal Antibody (eBio3E7 (3E7)), eBioscience™, Invitrogen™
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Catalog No. 14566582
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14-566-582 100 μg
50-131-15 500 μg
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Catalog No. 14-566-582 Supplier Invitrogen™ Supplier No. 14566582
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Description

Armenian Hamster Monoclonal Antibody

Description: Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved coverting the single chain presursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized. Applications Reported: This eBio3E7 (3E7) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistochemical staining. Applications Tested: This eBio3E7 (3E7) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.
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Specifications

Antigen Plexin-B2
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification Monoclonal
Clone eBio3E7 (3E7)
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene PLXNB2
Gene Accession No. B2RXS4
Gene Alias Debt; differentially expressed in brain tumors; dJ402G11.3; KIAA0315; MM1; MM1KIAA0315dJ402G11.3; Nbla00445; PLEXB2; plexin B2; plexin-B2; PLXNB2
Gene Symbols PLXNB2
Host Species Armenian Hamster
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140570
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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