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PLK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
$395.30
Specifications
| Antigen | PLK1 |
|---|---|
| Concentration | 0.16 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Conjugate | Unconjugated |
| Format | Liquid |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-172-6194
|
Proteintech Group Inc
103051AP150UL |
150 μL |
Each for $395.30
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Description
PLK1 is a Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1. Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.Specifications
| PLK1 | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Polyclonal | |
| -20°C |
| 0.16 mg/mL | |
| Unconjugated | |
| Rabbit | |
| Human, Mouse, Rat | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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