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Invitrogen™ PLP1 Monoclonal Antibody (538CT16.5.4)
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Catalog No. PIMA537605
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400 μL
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PIMA537605 400 μL
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Catalog No. PIMA537605 Supplier Invitrogen™ Supplier No. MA537605
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Mouse Monoclonal Antibody

PLP1 Monoclonal Antibody for Western Blot

PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLP1
Applications Western Blot
Classification Monoclonal
Clone 538CT16.5.4
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PLP1
Gene Accession No. P60201, P60203
Gene Alias DM20; GPM6C; HLD1; jimpy; jp; lipophilin; lipophilin (aa 129 to 276); major myelin proteolipid protein; MMPL; msd; Myelin proteolipid protein; myelin synthesis deficiency; PLP; PLP/DM20; Plp1; PMD; proteolipid; proteolipid protein; proteolipid protein (myelin) 1; Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated); Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein 1; proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein, lipophilin; rsh; rump shaker; SPG2
Gene Symbols PLP1
Host Species Mouse
Immunogen KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of rat PIp1.
Purification Method Euglobulin precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24943, 5354
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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