Invitrogen™ PLP1 Polyclonal Antibody

Catalog No.	Quantity
PIPA5117487	100 μg

Catalog No. PIPA5117487 Supplier Invitrogen™ Supplier No. PA5117487

Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.

Specifications

• Antigen: PLP1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene: PLP1
• Gene Accession No.: P60201
• Gene Alias: DM20; GPM6C; HLD1; jimpy; jp; lipophilin; lipophilin (aa 129 to 276); major myelin proteolipid protein; MMPL; msd; Myelin proteolipid protein; myelin synthesis deficiency; PLP; PLP/DM20; Plp1; PMD; proteolipid; proteolipid protein; proteolipid protein (myelin) 1; Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated); Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein 1; proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein, lipophilin; rsh; rump shaker; SPG2
• Gene Symbols: PLP1
• Host Species: Rabbit
• Immunogen: Recombinant Human Myelin proteolipid protein (143-197aa).
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5354
• Target Species: Human
• Content And Storage: -20°C or -80°C if preferred
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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