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Invitrogen™ PNK Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA19085
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Anti-human Polynucleotide Kinase Mouse Monoclonal Antibody recognizes polynucleotide kinase (PNK), a 57 kDa nuclear enzyme implicated in DNA strand repair processes that occur during DNA replication and recombination, or in response to DNA damaging agents. PNK targets the DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation events. During strand breakage in human cells, normal PNK associates with other nuclear proteins to prepare the DNA termini for the enzymatic actions of DNA polymerase-beta and DNA ligase III. PNK is a key functional component in maintaining the genetic stability of human cells.
Specifications
PNK | |
Polyclonal | |
Unconjugated | |
Pnkp | |
1810009G08Rik; 2'(3')-polynucleotidase; AOA4; bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; EIEE10; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP); MCSZ; phosphatase/kinase; PKNP; PNK; PNKP; Polynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase; polynucleotide kinase 3'- phosphatase; polynucleotide kinase 3'-phosphatase; polynucleotide kinase-3'-phosphatase | |
Goat | |
Ammonium Sulfate Precipitation | |
RUO | |
11284 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
Q96T60 | |
Pnkp | |
Synthetic peptide corresponding to the C terminus amino acids EPRLGRLYCQFSEG (aa 508-521). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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