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Invitrogen™ PNK Recombinant Rabbit Monoclonal Antibody (JE64-21)
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Catalog No. PIMA544764 Shop All Thermo Scientific Products
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PIMA544764 100 μL
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Catalog No. PIMA544764 Supplier Invitrogen™ Supplier No. MA544764
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Description

Rabbit Recombinant Monoclonal Antibody

PNK Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Anti-human Polynucleotide Kinase Mouse Monoclonal Antibody recognizes polynucleotide kinase (PNK), a 57 kDa nuclear enzyme implicated in DNA strand repair processes that occur during DNA replication and recombination, or in response to DNA damaging agents. PNK targets the DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation events. During strand breakage in human cells, normal PNK associates with other nuclear proteins to prepare the DNA termini for the enzymatic actions of DNA polymerase-beta and DNA ligase III. PNK is a key functional component in maintaining the genetic stability of human cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PNK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE64-21
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Pnkp
Gene Accession No. Q96T60
Gene Alias 1810009G08Rik; 2'(3')-polynucleotidase; AOA4; bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; EIEE10; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP); MCSZ; phosphatase/kinase; PKNP; PNK; PNKP; Polynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase; polynucleotide kinase 3'- phosphatase; polynucleotide kinase 3'-phosphatase; polynucleotide kinase-3'-phosphatase
Gene Symbols Pnkp
Host Species Rabbit
Immunogen Synthetic peptide within Human PNKP aa 51-100/521.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11284
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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