Invitrogen™ PNMA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561622

Catalog No. PIPA561622

Description

Immunogen sequence: PRPPARITGV GAVPLPASGN SFDVRPSQGY RRRRGRGQHR RGGVARAGSR GSRKRKRHTF CYSCG Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 50%.

The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. There are reports of the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PNMA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PNMA3
• Gene Alias: MA3; MA5; Paraneoplastic antigen Ma3; paraneoplastic antigen Ma3 homolog; paraneoplastic cancer-testis-brain antigen; paraneoplastic Ma antigen 3; PNMA3; RGD1563752
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29944
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UL41
• Gene Symbols: PNMA3
• Immunogen: Recombinant protein corresponding to Human PNMA3. Recombinant protein control fragment (Product #RP-100484).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov