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Invitrogen™ PODN Polyclonal Antibody
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Catalog No. PIPA547446
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100 μg
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PIPA547446 100 μg
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Catalog No. PIPA547446 Supplier Invitrogen™ Supplier No. PA547446
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Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human Podocan is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Non-collagenous proteins of the small leucine-rich repeat (SLR) protein family are considered important components of the extracellular matrix. The extracellular matrix plays an integral role in the pivotal processes of development, tissue repair and metastasis by regulating cell proliferation, differentiation, adhesion and migration. Podocan, also known as PCAN, SLRR5A or PODN, is a 613 amino acid secreted protein belonging to the small leucine-rich proteoglycan (SLRP) family and the class V subfamily. Expressed in kidney, heart, liver, pancreas and vascular smooth muscle cells, Podocan exists as three alternatively spliced isoforms containing twenty LRR (leucine-rich repeats), a unique N-terminal cysteine-rich cluster pattern and a highly acidic C-terminal domain. Podocan is considered a glycoprotein containing N-linked oligosaccharides that may be involved in growth regulation in cardiovascular tissues. Encoded by a gene located on human chromosome 1, Podocan interacts type I collagen (COL1).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PODN
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Podn
Gene Accession No. Q7TQ62
Gene Alias 9430070G18; Pcan; Podn; Podocan; podocan proteoglycan; PRO332; SLRR5A; UNQ293; UNQ293/PRO332
Gene Symbols Podn
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Podocan Val24-Arg611.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 242608
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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