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Invitrogen™ POLE3 Polyclonal Antibody
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Catalog No. PIPA583889
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100 μL
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PIPA583889 100 μL
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Catalog No. PIPA583889 Supplier Invitrogen™ Supplier No. PA583889
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAERPEDLNL PNAVITRIIK EALPDGVNIS KEARSAISRA ASVFVLYATS CANNFAMKGK RKTLN Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLE3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLE3
Gene Accession No. Q9NRF9
Gene Alias 1810034K18Rik; arsenic transactivated protein; arsenic-transactivated protein; AsTP; CHARAC17; CHRAC 17; CHRAC17; CHRAC-17; Chromatin accessibility complex 17 kDa protein; DNA polymerase epsilon 3, accessory subunit; DNA polymerase epsilon p17 subunit; DNA polymerase epsilon subunit 3; DNA polymerase epsilon subunit p17; DNA polymerase epsilon, subunit 3; DNA polymerase II subunit 3; DNA-directed DNA polymerase epsilon 3; histone fold protein CHRAC17; huCHRAC17; NF-YB-like protein; p17; Pole3; polymerase (DNA directed), epsilon 3 (p17 subunit); polymerase (DNA directed), epsilon 3, accessory subunit; polymerase (DNA) epsilon 3, accessory subunit; YBL1; YB-like protein 1
Gene Symbols POLE3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POLE3. Recombinant protein control fragment (Product #RP-100962).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54107
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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