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PolH Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501559838
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Quantity:
100 μL
Catalog No. Quantity
50-155-9838 100 μL
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Catalog No. 50-155-9838

Supplier: Bethyl Laboratories, Inc A301230A

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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum.

Specifications

Antigen PolH
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene POLH
Gene Accession No. Q9Y253
Gene Alias RAD30, RAD30A, XP-V, XPV, DNA polymerase eta, RAD30 homolog A, xeroderma pigmentosum variant type protein
Gene Symbols POLH
Host Species Rabbit
Immunogen Between 640 and 690
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5429
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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