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Invitrogen™ POLR1C Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA546750
Description
Peptide sequence: VRNVHTTDFP GNYSGYDDAW DQDRFEKNFR VDVVHMDENS LEFDMVGIDA Sequence homology: Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%.
RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription. RPA16, RPA40 and RPA135 are subunits of Pol I that associate with each other at an early stage of RNA Pol I assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
Specifications
POLR1C | |
Polyclonal | |
Unconjugated | |
POLR1C | |
40kDa; AA409007; AA959927; Ac2-127; AC40; AL024089; DNA-directed RNA polymerase I subunit C; DNA-directed RNA polymerases I and III 40 kDa polypeptide; DNA-directed RNA polymerases I and III subuni RPAC1-like protein; DNA-directed RNA polymerases I and III subunit RPAC1; HLD11; Polr1c; POLR1E; polymerase (RNA) I polypeptide C; polymerase (RNA) I polypeptide C, 30kDa; polymerase (RNA) I subunit C; RNA polymerase 1-1; RNA polymerase 1-1 (40 kDa subunit); RNA polymerase I 140 kDa subunit; RNA polymerase I and III subunit C; RNA polymerase I subunit; RNA polymerase I subunit C; RNA polymerase subunit I; RNA polymerases I and III subunit AC1; RPA39; RPA40; RPA5; RPAC1; RPC40; Rpo1-1; TCS3; Unknown (protein for MGC:134521); zgc:65973 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
9533 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
O15160 | |
POLR1C | |
Synthetic peptide directed towards the N-terminal of human POLR1C (aa 21-70). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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