Invitrogen™ POLR1C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587402

Catalog No. PIPA587402

Description

Immunogen sequence: MAASQAVEEM RSRVVLGEFG VRNVHTTDFP GNYSGYDDAW DQDRFEKNFR VDVVHMDENS LEFDMVGIDA AIANAFRRIL LAEVPTMAVE KVLVYNNTSI VQDEILAHRL GLIPIHADPR LFEYRNQGDE EGTEIDTLQF RLQVRCTRNP HAAKDSSDPN ELYVNHKVYT RHMTWIPLGN QADLFPEGTI RPVHDDILIA; Positive Samples: K-562, 293T, MCF7; Cellular Location: Nucleus.

RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription. RPA16, RPA40 and RPA135 are subunits of Pol I that associate with each other at an early stage of RNA Pol I assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).

Specifications

• Antigen: POLR1C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR1C
• Gene Alias: 40kDa; AA409007; AA959927; Ac2-127; AC40; AL024089; DNA-directed RNA polymerase I subunit C; DNA-directed RNA polymerases I and III 40 kDa polypeptide; DNA-directed RNA polymerases I and III subuni RPAC1-like protein; DNA-directed RNA polymerases I and III subunit RPAC1; HLD11; Polr1c; POLR1E; polymerase (RNA) I polypeptide C; polymerase (RNA) I polypeptide C, 30kDa; polymerase (RNA) I subunit C; RNA polymerase 1-1; RNA polymerase 1-1 (40 kDa subunit); RNA polymerase I 140 kDa subunit; RNA polymerase I and III subunit C; RNA polymerase I subunit; RNA polymerase I subunit C; RNA polymerase subunit I; RNA polymerases I and III subunit AC1; RPA39; RPA40; RPA5; RPAC1; RPC40; Rpo1-1; TCS3; Unknown (protein for MGC:134521); zgc:65973
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9533
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Western Blot
• Concentration: 0.98 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O15160
• Gene Symbols: POLR1C
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human POLR1C (NP_9760351).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov