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Invitrogen™ POLR1C Polyclonal Antibody
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Catalog No. PIPA587402
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100 μL
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PIPA587402 100 μL
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Catalog No. PIPA587402 Supplier Invitrogen™ Supplier No. PA587402
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAASQAVEEM RSRVVLGEFG VRNVHTTDFP GNYSGYDDAW DQDRFEKNFR VDVVHMDENS LEFDMVGIDA AIANAFRRIL LAEVPTMAVE KVLVYNNTSI VQDEILAHRL GLIPIHADPR LFEYRNQGDE EGTEIDTLQF RLQVRCTRNP HAAKDSSDPN ELYVNHKVYT RHMTWIPLGN QADLFPEGTI RPVHDDILIA; Positive Samples: K-562, 293T, MCF7; Cellular Location: Nucleus.

RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription. RPA16, RPA40 and RPA135 are subunits of Pol I that associate with each other at an early stage of RNA Pol I assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR1C
Applications ELISA, Western Blot, Western Blot
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene POLR1C
Gene Accession No. O15160
Gene Alias 40kDa; AA409007; AA959927; Ac2-127; AC40; AL024089; DNA-directed RNA polymerase I subunit C; DNA-directed RNA polymerases I and III 40 kDa polypeptide; DNA-directed RNA polymerases I and III subuni RPAC1-like protein; DNA-directed RNA polymerases I and III subunit RPAC1; HLD11; Polr1c; POLR1E; polymerase (RNA) I polypeptide C; polymerase (RNA) I polypeptide C, 30kDa; polymerase (RNA) I subunit C; RNA polymerase 1-1; RNA polymerase 1-1 (40 kDa subunit); RNA polymerase I 140 kDa subunit; RNA polymerase I and III subunit C; RNA polymerase I subunit; RNA polymerase I subunit C; RNA polymerase subunit I; RNA polymerases I and III subunit AC1; RPA39; RPA40; RPA5; RPAC1; RPC40; Rpo1-1; TCS3; Unknown (protein for MGC:134521); zgc:65973
Gene Symbols POLR1C
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human POLR1C (NP_9760351).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9533
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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