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Invitrogen™ POLR2K Polyclonal Antibody
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Catalog No. PIPA5117366
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100 μL
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PIPA5117366 100 μL
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Catalog No. PIPA5117366 Supplier Invitrogen™ Supplier No. PA5117366
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Description

Rabbit Polyclonal Antibody

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RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR2K
Applications Western Blot
Classification Polyclonal
Concentration 1.61 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene POLR2K
Gene Accession No. P53803
Gene Alias ABC10-alpha; DNA directed RNA polymerases I, II, and III 7.0 kda polypeptide; DNA-directed RNA polymerase II subunit K; DNA-directed RNA polymerases I, II, and III subunit RPABC4; hRPB7.0; hsRPB10a; MafY; mCG145114-like; metallothionein-I gene transcription activator; Mt1a; POLR2K; polymerase (RNA) II (DNA directed) polypeptide K; polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa; polymerase (RNA) II subunit K; RNA polymerase II 7.0 kDa subunit; RNA polymerase II subunit K; RNA polymerases I, II, and III subunit ABC4; RPABC4; RPB10alpha; RPB12; RPB7.0
Gene Symbols POLR2K
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human POLR2K. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5440
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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