POLR3H Monoclonal Antibody (OTI5A12), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-2794	100 μL

Catalog No. 50-168-2794 Supplier OriGene Supplier No. TA809442

Description

Mouse Monoclonal Antibody

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.

Specifications

• Antigen: POLR3H
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5A12
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: POLR3H
• Gene Accession No.: Q9Y535
• Gene Alias: RPC22.9, RPC8
• Gene Symbols: POLR3H
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human POLR3H produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 171568
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a