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Invitrogen™ POLR3H Polyclonal Antibody
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Catalog No. PIPA561325
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100 μL
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PIPA561325 100 μL
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Catalog No. PIPA561325 Supplier Invitrogen™ Supplier No. PA561325
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GFFDDILIPP ESLQQPAKFD EAEQVWVWEY ETEEGAHDLY MDTGEEIRFR VVDESFVDTS PTGPSSADAT TSSEELPKKE APYTLVG Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR3H
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLR3H
Gene Accession No. Q9Y535
Gene Alias 5031409G22Rik; DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide; DNA-directed RNA polymerase III subunit H; DNA-directed RNA polymerase III subunit RPC8; KIAA1665; POLR3H; polymerase (RNA) III (DNA directed) polypeptide H; polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); polymerase (RNA) III subunit H; RNA nucleotidyltransferase (DNA-directed); RNA polymerase III subunit 22.9 kDa subunit; RNA polymerase III subunit C7; RNA polymerase III subunit C8; RNA polymerase III subunit H; RPC22.9; RPC8
Gene Symbols POLR3H
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POLR3H. Recombinant protein control fragment (Product #RP-91548).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171568
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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