Invitrogen™ POM121 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536498

Catalog No. PIPA536498

Description

This antibody detects endogenous protein at a molecular weight of 121 kDa. Purity is >95% by SDS-PAGE.

POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM 121A), NUP121 (nucleoporin Nup121) or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spiced isoforms and belongs to the POM121 family. Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to nucleus membrane and endoplasmic reticulum membrane. An essential component of the nuclear pore complex (NPC), POM121 is mandatory for nuclear envelope formation and may play a role in biogenesis of the NPC. POM121 associates with the central spoke ring complex and is involved in anchoring components of the pore complex to the pore membrane by way of its F-X-F-G repeat-containing domain. POM121 overexpression induces the formation of cytoplasmic annulate lamellae (AL).

Specifications

• Antigen: POM121
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POM121B
• Gene Alias: 2610027A18Rik; C80273; KIAA0618; mKIAA0618; Nuclear envelope pore membrane protein POM 121; nuclear envelope pore membrane protein POM 121A; nuclear envelope pore membrane protein POM 121C; nuclear pore membrane glycoprotein 121 kD; nuclear pore membrane protein 121; nuclear pore membrane protein 121 kDa; nuclear pore membrane protein 121-2; nucleoporin Nup121; Nup121; p145; Pom121; POM121 membrane glycoprotein; POM121 membrane glycoprotein C; POM121 transmembrane nucleoporin; POM121 transmembrane nucleoporin C; POM121-2; POM121A; POM121B; POM121C; Pore membrane protein of 121 kDa; pore membrane protein of 121 kDa C
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100101267, 100288540, 107939, 113975, 9883
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A6NF01, A8CG34, P52591, Q8K3Z9, Q96HA1
• Gene Symbols: POM121, POM121B, POM121C
• Immunogen: Synthetic peptide corresponding to the C-terminual of human POM121.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG