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Invitrogen™ POM121 Polyclonal Antibody
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Catalog No. PIPA536498
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100 μL
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PIPA536498 100 μL
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Catalog No. PIPA536498 Supplier Invitrogen™ Supplier No. PA536498
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 121 kDa. Purity is >95% by SDS-PAGE.

POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM 121A), NUP121 (nucleoporin Nup121) or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spiced isoforms and belongs to the POM121 family. Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to nucleus membrane and endoplasmic reticulum membrane. An essential component of the nuclear pore complex (NPC), POM121 is mandatory for nuclear envelope formation and may play a role in biogenesis of the NPC. POM121 associates with the central spoke ring complex and is involved in anchoring components of the pore complex to the pore membrane by way of its F-X-F-G repeat-containing domain. POM121 overexpression induces the formation of cytoplasmic annulate lamellae (AL).
TRUSTED_SUSTAINABILITY

Specifications

Antigen POM121
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene POM121B
Gene Accession No. A6NF01, A8CG34, P52591, Q8K3Z9, Q96HA1
Gene Alias 2610027A18Rik; C80273; KIAA0618; mKIAA0618; Nuclear envelope pore membrane protein POM 121; nuclear envelope pore membrane protein POM 121A; nuclear envelope pore membrane protein POM 121C; nuclear pore membrane glycoprotein 121 kD; nuclear pore membrane protein 121; nuclear pore membrane protein 121 kDa; nuclear pore membrane protein 121-2; nucleoporin Nup121; Nup121; p145; Pom121; POM121 membrane glycoprotein; POM121 membrane glycoprotein C; POM121 transmembrane nucleoporin; POM121 transmembrane nucleoporin C; POM121-2; POM121A; POM121B; POM121C; Pore membrane protein of 121 kDa; pore membrane protein of 121 kDa C
Gene Symbols POM121, POM121B, POM121C
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the C-terminual of human POM121.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100101267, 100288540, 107939, 113975, 9883
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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