Gibco™ Porcine IL-2, AOF Recombinant Protein

Description

Recombinant Protein

Animal Origin Free Reconstitute with sterile water at 0.1 mg/mL.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Specifications

• Accession Number: P26891
• Concentration: 0.1 mg/mL
• For Use With (Application): Control
• Formulation: 10 mM sodium phosphate with no preservative; pH 7.5
• Gene ID (Entrez): 396868
• Molecular Weight (g/mol): 15.3 kDa
• Name: Porcine IL-2, AOF
• Quantity: 1 mg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: ≤1 EU/ μg
• Gene Alias: aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
• Common Name: IL-2
• Gene Symbol: IL2
• Biological Activity: ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of CTLL-2 cells.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MAPTSSSTKN TKKQLEPLLL DLQLLLKEVK NYENADLSRM LTFKFYMPKQ ATELKHLQCL VEELKALEGV LNLGQSKNSD SANIKESMNN INVTVLELKG SETSFKCEYD DETVTAVEFL NKWITFCQSI YSTLT
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: >95% by SDS-Page