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Gibco™ Porcine IL-2, AOF Recombinant Protein

Catalog No. PIRP87807
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PIRP87807 500 μg
PIRP87803 100 μg
PIRP87805 1 mg
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Catalog No. PIRP87807 Supplier Gibco™ Supplier No. RP87807
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Description

Recombinant Protein

Animal Origin Free Reconstitute with sterile water at 0.1 mg/mL.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P26891
Concentration 0.1 mg/mL
For Use With (Application) Control
Formulation 10 mM sodium phosphate with no preservative; pH 7.5
Gene ID (Entrez) 396868
Molecular Weight (g/mol) 15.3 kDa
Name Porcine IL-2, AOF
Quantity 500 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration ≤1 EU/ μg
Gene Alias aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Common Name IL-2
Gene Symbol IL2
Biological Activity ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of CTLL-2 cells.
Conjugate Unconjugated
Recombinant Recombinant
Sequence MAPTSSSTKN TKKQLEPLLL DLQLLLKEVK NYENADLSRM LTFKFYMPKQ ATELKHLQCL VEELKALEGV LNLGQSKNSD SANIKESMNN INVTVLELKG SETSFKCEYD DETVTAVEFL NKWITFCQSI YSTLT
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade >95% by SDS-Page
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