Gibco™ Porcine IL-4, AOF Recombinant Protein

Catalog No.	Quantity
PIRP87795	1 mg
PIRP87793	100 μg
PIRP87797	500 μg

Catalog No. PIRP87795 Supplier Gibco™ Supplier No. RP87795

Description

Recombinant Protein

Animal Origin Free Reconstitution: Sterile Water at 0.1 mg/mL

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Specifications

• Accession Number: Q04745
• Concentration: 0.1 mg/mL
• For Use With (Application): Bioactivity
• Formulation: 10mM sodium phosphate with no preservative; pH 7.5
• Gene ID (Entrez): 397225
• Molecular Weight (g/mol): 12.7 kDa
• Name: Porcine IL-4, AOF
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 1 mg
• Source: E. coli
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: ≤0.1 EU/μg
• Gene Alias: B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
• Common Name: IL-4
• Gene Symbol: Il4
• Biological Activity: ED50 = 2 ng/mL; determined by the dose-dependent proliferation of TF-1 cells.
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MHKCDITLQE IIKTLNILTA RKNSCMELPV TDVFAAPENT TEKETFCRAS TVLRHIYRHH TCMKSLLSGL DRNLSSMANM TCSVHEAKKS TLKDFLERLK TIMKEKYSKC
• Content And Storage: -20°C
• Activity: ED50 ≤ 2 ng/mL; determined by the dose-dependent proliferation of TF-1 cells.
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥95% by SDS-Page