PP2A alpha Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA594942

Catalog No. PIPA594942

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL.

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Specifications

• Antigen: PP2A alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP2CA
• Gene Alias: B55-GAMMA, hypothetical protein, IMYPNO, IMYPNO1, Methyl-PPP2CA, MGC33570, PP2A, PP2A alpha, PP2A C terminal, PP2A L9, PP2A Leucine 9, Pp2a1, PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, Ppp2ca, PR52, PR55G, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, protein phosphatase 2 catalytic subunit alpha, protein phosphatase 2, catalytic subunit, alpha isoform, protein phosphatase 2, catalytic subunit, alpha isozyme, protein phosphatase 2,catalytic subunit alpha isozyme, protein phosphatase 2A alpha subunit, protein phosphatase 2A catalytic subunit alpha isoform, protein phosphatase 2a, catalytic subunit, alpha isoform, protein phosphatase type 2A catalytic subunit, protein phosphatase-2A, protein phosphatase-2A-alpha, R75353, replication protein C, RP-C, serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, unnamed protein product
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19052, 24672, 5515
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
• Gene Accession No.: P63330, P63331, P67775
• Gene Symbols: PPP2CA
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A-alpha (6-20aa FTKELDQWIEQLNEC).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov