Invitrogen™ PPAP2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542116

Catalog No. PIPA542116

Description

Peptide sequence: DPDWSKINCS DGYIEYYICR GNAERVKEGR LSFYSGHSSF SMYCMLFVAL Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.

Specifications

• Antigen: PPAP2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLPP1
• Gene Alias: 35 kDa PAP; Hic53; Hpic53; hydrogen peroxide inducible protein 53; Hydrogen peroxide-inducible protein 53; Lipid phosphate phosphohydrolase 1; lipid phosphate phosphohydrolase 1a; LLP1a; Lpp1; LPP-1; magnesium-independent type 2 phosphatidic acid phosphatase; mPAP; PAP2; PAP2A; PAP-2a; PAP2a2; PAP2-alpha; PAP2alpha2; PAPalpha1; phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a; phosphatidic acid phosphatase 2a2; phosphatidic acid phosphatase type 2A; phosphatidic acid phosphohydrolase type 2a; phospholipid phosphatase 1; Plpp1; Ppap2a; PPAP2A; LPP1; type-2 phosphatidic acid phosphatase alpha; Unknown (protein for MGC:133873); WUN
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 19012, 8611
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O14494, Q61469
• Gene Symbols: PLPP1
• Immunogen: Synthetic peptide directed towards the middle region of human PPAP2A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov