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Invitrogen™ PPAR alpha Polyclonal Antibody
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Catalog No. 424600
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Catalog No. Quantity
42-460-0 100 μg
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Catalog No. 42-460-0 Supplier Invitrogen™ Supplier No. 424600
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Description

Rabbit Polyclonal Antibody

PPAR alpha Polyclonal Antibody for Western Blot

Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPAR's). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPAR's are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPAR's can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements. PPAR, like several other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPAR alpha
Applications Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene PPARA
Gene Accession No. P23204, Q07869
Gene Alias 4933429D07Rik; AW742785; hPPAR; I79_022392; MGC2237; MGC2452; Nr1c1; nuclear hormone receptor; nuclear receptor; nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor alpha; peroxisome proliferative activated receptor, alpha; peroxisome proliferative activated receptor, alpha isoform 1; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; peroxisome proliferator-activated receptor alpha; PPAR; PPAR ALPHA; Ppara; PPARALPHA; PPAR-alpha; proliferator-activated receptor alpha; transcription factor belonging to the nuclear receptor superfamily
Gene Symbols PPARA
Host Species Rabbit
Immunogen specific to Human PPAR alpha.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19013, 5465
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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