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Invitrogen™ PPM1B Polyclonal Antibody
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Catalog No. PIPA582557
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100 μL
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PIPA582557 100 μL
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Catalog No. PIPA582557 Supplier Invitrogen™ Supplier No. PA582557
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KRNVIEAVYS RLNPHRESDG ASDEAEESGS QGKLVEALRQ MRINHRGNYR QLLEEMLTSY RLAKVEGEES PAEPAATATS SNSDAGNPVT MQESHTESES GLAEL Highest antigen sequence indentity to the following orthologs: Mouse - 80%, Rat - 85%.

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPM1B
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PPM1B
Gene Accession No. O75688
Gene Alias EGK_05287; Pp2c2; PP2CB; PP2CBETA; PP2C-beta; PP2C-beta-X; PPC2BETAX; PPM1B; Pppm1b; Protein phosphatase 1B; protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform; protein phosphatase 1B, magnesium dependent, beta isoform; protein phosphatase 2C isoform beta; protein phosphatase 2C-like protein; Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform; Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform; protein phosphatase, Mg2+/Mn2+ dependent 1B; protein phosphatase, Mg2+/Mn2+ dependent, 1B; Ser/Thr protein phosphatase type 2C beta 2 isoform
Gene Symbols PPM1B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPM1B. Recombinant protein control fragment (Product #RP-91561).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5495
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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