Invitrogen™ PPM1F Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112664

Catalog No. PIPA5112664

Description

PPM1F Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.

Specifications

• Antigen: PPM1F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPM1F
• Gene Alias: 1110021B16Rik; 4933427B07Rik; Ca(2+)/calmodulin-dependent protein kinase phosphatase; calcium/calmodulin-dependent protein kinase phosphatase; caM-kinase phosphatase; CAMKP; CaMKPase; FEM-2; hFem-2; KIAA0015; mKIAA0015; Partner of PIX 2; partner of PIX2; POPX2; PP2C phosphatase; Ppm1f; Protein fem-2 homolog; protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing); protein phosphatase, Mg2+/Mn2+ dependent 1F; protein phosphatase, Mg2+/Mn2+ dependent, 1F
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 68606, 9647
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 4.07 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P49593, Q8CGA0
• Gene Symbols: PPM1F
• Immunogen: Recombinant Human Protein phosphatase 1F protein (1-76AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov