Invitrogen™ PPP1R7 Monoclonal Antibody (OTI4F9)

Catalog No.	Quantity
PIMA524968	100 μL

Catalog No. PIMA524968

Supplier: Invitrogen™ MA524968

Description

Mouse Monoclonal Antibody

PPP1R7 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.

Specifications

• Antigen: PPP1R7
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: OTI4F9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: PPP1R7
• Gene Accession No.: Q15435, Q5HZV9
• Gene Alias: 2310014J01Rik; hypothetical protein LOC560323; im:7136431; Ppp1r7; Protein phosphatase 1 regulatory subunit 22; protein phosphatase 1 regulatory subunit 7; protein phosphatase 1, regulatory (inhibitor) subunit 7; protein phosphatase 1, regulatory subunit 7; protein phosphatase-1 regulatory subunit 7; Sds22; testis secretory sperm-binding protein Li 210a; zgc:123325
• Gene Symbols: PPP1R7
• Host Species: Mouse
• Immunogen: Full length human recombinant protein of PPP1R7 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100855698, 301618, 5510
• Target Species: Human, Rat, Canine
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1