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PPP4R2 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501558581
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50-155-8581 100 μL
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Catalog No. 50-155-8581 Supplier Bethyl Laboratories, Inc Supplier No. A300838A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on ′Ser-140′ (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Specifications

Antigen PPP4R2
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PPP4R2
Gene Accession No. Q0VGB7, Q9NY27
Gene Alias PP4R2, serine/threonine-protein phosphatase 4 regulatory subunit 2
Gene Symbols PPP4R2
Host Species Rabbit
Immunogen Between 370 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151987, 232314
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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