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Invitrogen™ PPP6C Polyclonal Antibody
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Catalog No. 01674132
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Catalog No. Quantity
01-674-132 100 μg
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Catalog No. 01-674-132 Supplier Invitrogen™ Supplier No. PA112399
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Description

Rabbit Polyclonal Antibody

PPP6C Polyclonal Antibody for Western Blot, IHC, IP

Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin. Artemis is a single-strand-specific 5' to 3' exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5' and 3' overhangs and hairpins. These activities are essential for V(D)J recombination and for the 5' and 3' overhang processing in nonhomologous DNA end joining.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP6C
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene Ppp6c
Gene Accession No. O00743, Q64620, Q9CQR6
Gene Alias 2310003C10Rik; ANKRD33; FLJ34236; PP6; PP6C; PPP6; PPP6C; Ppv; PP-V; protein phosphatase 6 catalytic subunit; protein phosphatase 6, catalytic subunit; protein phosphatase V; serine/threonine protein phosphatase catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit; Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed; UNQ5837
Gene Symbols Ppp6c
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171121, 511058, 5537, 67857
Target Species Human, Mouse, Rat, Bovine
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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